Paranoia:  Psychological, neurological, physiological or oxidative stress?

There are many different psychological theories regarding the presentation of paranoia.   There are also different psychiatric and physiological theories for paranoia.  In alternative medicine, a number of excess and deficiences of neurotransmitters, vitamins and toxicities are both recognized and used to eliminate paranoia.  Oxidative stress and low glutahtione appear to be common factors in paranoia.

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The following is an article summarizing different perspectives concerning the expression of paranoia.

Paranoia

Paranoia is a symptom rather than a specific disease condition, and is associated with a number of biochemical imbalances. First of all, it is clear that paranoia generally involves a genetic predisposition. In my experience paranoia usually involves either highly elevated norepinephrine or diminished GABA levels. The recipe for paranoid schizophrenia is (1) overproduction of dopamine due to an innate tendency for overmethylation, (2) excessive conversion of dopamine to norepinephrine due to high copper levels, and (3) depressed levels of GABA (which tends to quench the paranoia & anxiety associated with elevated norepinaphrine. The patients are usually afflicted with multiple medications which can provide some relief, albeit with very unpleasant side effects. Complementary medicine techniques to balance body/brain chemistry may involve therapies using folates, zinc, manganese, and vitamins B-3, B-6, C, and E and can be very successful This treatment should be individualized to reflect the individual's array of chemical imbalances.... for best results. In many cases paranoia is exacerbated by estrogen therapy, environmental sources of copper, well-intentioned (but wrong) vitamin/mineral supplements, and/or chelation therapy. For females, paranoia tends to flare up during hormonal events including puberty, childbirth, and menopause. (Feb 10, 2003)

http://www.alternativementalhealth.com/articles/walshMP.htm