Is weight an issue for you? It sure seems to be an issue for a lot of people.

One way to help your body eliminate weight is to work with the weight managing hormones:

  • Leptin – increases sensation of satiety
    • as well as:
    • cholesystokinin (CCK)
    • glucagon-like peptide (GLP)Dr Holly Obesity
    • (PPY)
    • melancortin
  • Grehlin – increases sense of hunger
  • Adiponectin – regulates glucose levels and fatty acid breakdown
  • Cortisol – regulates blood glucose levels by inhibiting insulin production to prevent glucose from being stored
  • Insulin – helps to move sugar from the blood into your cells

Yes, they are all involved in weight management. But for many us, they are out of balance. Now there are all kinds of programs and magic pills out there that claim that they will increase or decrease the different hormones.

Unfortunately, these don’t work well. These hormones are also involved in a wide number of other functions as well. They need to be in a given balance with one another.

Leptin – released from white fat cells; when leptin is low, we eat more; so we need to keep it up; but too much leptin (secreted from all those fat cells) plugs up the leptin system causing leptin resistance; also involved in insulin secretion; growth hormone; brain function; immune system; thyroid & adrenal function; reproductive system

Grehlin – released in the stomach & small intestine, pancreas and brain. In addition to stimulating hunger, it also regulates growth hormone; regulates energy balance: increase food intake to reduce fat utilization; stimulates lactotroph and corticotroph function effecting the pituitary gonadal function (reproductive system); inhibits pro-inflammatory messengers; effects gastric motility (movement of bowel movement); and acid secretion; pancreatic hormone secretion; glucose metabolism.

Adiponectin – a protein hormone released from fat cells that regulates glucose; low levels precede declines in insulin sensitivity; improves insulin sensitivity in the liver; highly regulated in gut fat, increasing abdominal obesity; inversely correlated with levels of leptin & insulin; interactive with steroid hormones.

Cortisol – regulates many of the changes that occur in the body in response to stress; regulates blood glucose levels; metabolism; and the immune response; sex drive & menses; blood pressure; osteoporosis; muscle strength and mood/anxiety.

These hormones obviously have a huge impact on the body. So we need to make sure that the body can regulate them.

  • food restriction
  • exercise
  • weight loss

And what foods do we eat?

  • raw nuts and seeds
  • legumes
  • roots
  • cruciferous vegetables: Dr Holly healthy fat salad
    • argula
    • bok choy
    • broccoli
    • brussles sprouts
    • cauliflower
    • cabbage
    • kale
    • rutabaga
  • tomatoes
  • eggplant
  • green leafy vegatables

And what foods do we avoid?bad fats

  • bad fats
  • baking goods
  • candies
  • fructose products
  • simple carbs
  • sugars

Fruit high in fructose are also a challenge.

So we come back to what our Moms told us, “Eat your vegetables!”

Enjoy and have fun with them. For more information on health subjects,books signature image email

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In addition, you may want to sign up for the

You may also want to listen to the Whole Health Initiative on every Wednesday from 12 – 1 Noon.

Here’s to your health!

For more information, contact: Dr Holly at

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